Multiple Sclerosis

Cannabinoids are known to decrease spasms and cramps. Studies suggest that cannabinoids may offer some benefit as a treatment that does not affect the patient's cognitive status, as it happens with other treatments.

Medical Cannabis’ effects against multiple sclerosis:

  • Decrease muscle spasms.
  • Neuroprotector.
  • Analgesic.
  • Treatment for neuropathic pain.
  • No alteration of the cognitive state.

The role played by cannabidiol CBD as a coadjuvant treatment is essential to reduce muscle spasms developed by patients suffering from this disease. Likewise, it is proven that the medicinal properties of cannabinoids reduce pain, improve sleep disturbances, help to combat urinary incontinence problems and discomfort, among other symptoms that may be present.

Endocannabinoids have immunosuppressive and anti-inflammatory properties. Also, they potentiate the progression of T cells of the immune system to their Th2 phenotype, which helps to reduce the degree of immune deterioration in affected patients.

A study conducted at the University of Catania, Italy, analyzed the data of 1,534 patients from different centers dedicated to the treatment of multiple sclerosis. The investigation concluded that, after the first month of treatment with medical Cannabis administered as a spray, 61.9% of the patients showed a decrease in symptoms such as cramps or night spasms, among others.

According to the Consortium of Multiple Sclerosis Centers (CMSC) and its study “Complementary and Alternative Medicine: Controversial and unconventional therapies,” the impact on the cognitive abilities of medical cannabis is notoriously lower than the use of conventional therapy. With that in mind, new reports on the symptomatic improvement for stiffness, muscle spasms, neuropathic pain, sleep and bladder distension in patients with multiple sclerosis who treat their disease with cannabinoids, are emerging.


Multiple sclerosis, cannabis, and cognition: A structural MRI study, 2015. Kristoffer Romero; Bennis Pavisian; William R. Staines; Anthony Feinstein.
Attitudes to cannabis and patterns of use among Canadians with multiple sclerosis, 2016. Emma Banwell; Bennis Pavisian; Liesly Lee; Anthony Feinstein.
Cannabis and Multiple Sclerosis—The Way Forward, 2017. Thorsten Rudroff and Justin M. Honce.
The Use of Cannabis and Cannabinoids in Treating Symptoms of Multiple Sclerosis: a Systematic Review of Reviews, February 2018, 18:8. Suzanne Nielsen; Rada Germanos; Megan Weier; John Pollard; Louisa Degenhardt; Wayne Hall; Nicholas Buckley; Michael Farrell.

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