The usual treatment of glaucoma, one of the main causes of blindness in the world, consists in the administration of drugs that reduce intraocular pressure or drain the excess of aqueous humor.
Current studies suggest that cannabinoids can reduce intraocular pressure and could be used effectively in topical therapies for neurodegenerative diseases of the retina, either alone or combined with other drugs.
Cannabinoids are well tolerated after topical use, and they are attributed with a neuroprotective effect on the ganglion cells of the retina. Scientific observations indicate that endocannabinoids are relevant in ocular physiology, influencing on the maintenance of intraocular pressure, the physiology of photoreception and neurotransmission in the retina, as well as the neuroprotection of ganglion neurons of the retina.