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Glaucoma

Currently, the therapeutic effects of medical cannabis on glaucoma are being studied aiming to find therapeutic strategies to control cell death of the retina and prevent vision loss.

Medical Cannabis’ effects against glaucoma:

  • Peripheral and hypotensive vasodilator.
  • Hypotensor.
  • Reduction of intraocular pressure.

The usual treatment of glaucoma, one of the main causes of blindness in the world, consists in the administration of drugs that reduce intraocular pressure or drain the excess of aqueous humor.

Current studies suggest that cannabinoids can reduce intraocular pressure and could be used effectively in topical therapies for neurodegenerative diseases of the retina, either alone or combined with other drugs.

Cannabinoids are well tolerated after topical use, and they are attributed with a neuroprotective effect on the ganglion cells of the retina. Scientific observations indicate that endocannabinoids are relevant in ocular physiology, influencing on the maintenance of intraocular pressure, the physiology of photoreception and neurotransmission in the retina, as well as the neuroprotection of ganglion neurons of the retina.

 

Referencias:
Cannabinoids for treatment of glaucoma, 2016. Novack, Gary D.
Medical marijuana patient counseling points for health care professionals based on trends in the medical uses, efficacy, and adverse effects of cannabis-based pharmaceutical drugs, 2016. Jayesh R.ParmarPh.D.
Therapeutic potential of cannabis-related drugs; 2016. Stephen P.H.Alexander.
Cannabis use patterns and motives: A comparison of younger, middle-aged, and older medical cannabis dispensary patients; 2017. Nancy A. Haug
Therapeutic Benefit of Smoked Cannabis in Randomized Placebo?Controlled Studies; 2017. Lynneice L. Bowen; Aimee L. McRae?Clark.

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