The analgesic effect of cannabinoids is one of the best-characterized effects. Studies suggest that cannabinoids could offer some benefit, as a treatment against the pain suffered by people with fibromyalgia.

Medical Cannabis’ effects against fibromyalgia:

  • Cannabinoids decrease pain reactivity.
  • Activation of pathways of the descendent inhibitory system.
  • Treatment for chronic pain.
  • Treatment for neuropathic pain.
  • Analgesic effect.

Since fibromyalgia is difficult to control with analgesics, many patients seek to relieve their pain with alternative therapies such as cannabinoids for example. Although there are few clinical studies on the effect of medical cannabis on this disease, it has been shown that the consumption of cannabis derivatives has beneficial effects on some fibromyalgia symptoms, such as relief of pain and muscle stiffness, thus improving patients’ quality of life.

A 2008 study showed, after the administration of a synthetic cannabinoid for two weeks, a significant improvement in pain and numerous parameters associated with fibromyalgia.
In another 2011 study, after the administration of both vaporized and oral cannabis, an improvement in pain and stiffness, and an increase in the general well-being of the patient was observed.

Due to the therapeutic potential of cannabinoids in the treatment of fibromyalgia and the limited supply of existing effective treatments, numerous studies are being carried out to better understand both, the disease and its possible treatments.


Cannabinoids for fibromialgia, 2016. Brian Walitt; Petra Klose; Mary?Ann Fitzcharles; Tudor Phillips.
Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes, 2016. Ethan B. Russo.
Efficacy, tolerability and safety of cannabinoids in chronic pain associated with rheumatic diseases (fibromyalgia syndrome, back pain, osteoarthritis, rheumatoid arthritis), 2016. Der Schmerz.
Chapter e16 – Cannabis Use in Fibromyalgia, 2017. M.Farré; A.Farré; J.Fiz; M.Torrens.
Medical Cannabis for the Treatment of Fibromyalgia, 2018. Habib, George, MD, MPH; Artul, Suheil, MD.

See more diseases

See more